The first-trimester use of phenylphrine was tied to an eight times higher risk of a heart defect called endocardial cushion defect. Extended release: Take 120 mg every 12 hours or 240 mg every 24 hours. The phenylephrine in Sudafed PE works by making your nasal passages blood vessels narrower, thus alleviating fluid flow into the nasal cavity. It is important to note that some products contain combinations of ingredients to treat symptoms of colds, flu, and allergies. Pseudoephedrine and phenylephrine are pregnancy category C in all three trimesters of pregnancy. Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. Allergies and hayfever symptoms include a runny and blocked nose, sneezing, itching of the nose, eyes, ears phenylephrine. Nearly one in four pregnant women seeks relief from nasal congestion caused by upper respiratory tract infection, allergic rhinitis, or the common phenomenon known as pregnancy rhinitis. information and will only use or disclose that information as set forth in our notice of If you took a decongestant in the first trimester your child would have about a 2.7 in 1,000 chance of having a defect. The risks. Therapeutic Goods Administration. Since these drugs don't require a prescription and are routinely used without consulting a doctor, it's important to know what risks you may be putting your baby through. There are no controlled data in human pregnancy. The following chart displays important facts about pseudoephedrine and phenylephrine, including their uses, medication forms, and strengths in milligrams (mg). If phenylephrine is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. I recommend taking the highest effective dose for you of one or the other, not both. Take phenylephrine exactly as prescribed. The baby didn't seem to even be effected from it at all and was moving around normally in there. But know that there is little risk of birth defects. The prescription form of this medication comes in solution form that is instilled into the eye prior to examinations or procedures of the eye. Pseudoephedrine and phenylephrine are medications that can help alleviate nasal congestion. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. PromethazinePhenothiazines, such as promethazine (contained in some of these combination medicines [e.g., Phenergan-D]), have been shown to cause Tell your doctor if you have any side effect that bothers you or that does not go away. PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride injection, DailyMed: Current Medication Information; U.S. National Library of Medicine. Individuals can find phenylephrine in various over-the-counter medications for cold, flu, and allergy symptoms. In the meantime, use another method of birth control, such as condoms. information submitted for this request. If you do conceive while taking a progestin-only birth control pill, sometime called the minipill, there is a slightly higher chance that the pregnancy will be ectopic. These drugs work by constricting blood vessels within the nose and sinuses, which allow people to breathe more easily. Cold-like symptoms may make your nasal passage extremely congested. Especially tell your doctor if you: Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Phenylephrine belongs to a group of drugs called sympathomimetic agents. His team worked with a large collection of data on babies born with birth defects between 1993 and 2010. information is beneficial, we may combine your email and website usage information with Toxicology Data Network. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. vomiting. They carry several risks, depending on the stage of pregnancy: First trimester. 12 The American College of Obstetricians and Gynecologists We all have encountered such complications countless times since childhood and may know some real-life hacks that have been used to deal with nasal congestion. What are the best nasal decongestants for different ages? (2020). I did however, get the best night's sleep I have had in a month. However, if overdose is suspected, seek emergency medical attention. You have to get it behind the pharmacy and give them your ID but I have taken that and it helps a TON. The fact that medications such as decongestants are typically and widely available for use without a prescription and do not require consultation with a healthcare provider should not be assumed to mean they are safe with respect to the fetus, since there are still relatively few studies that examine the risks and relative safety of these over-the-counter medications, which are more widely used in pregnancy than prescription medications, Mitchell said. These may include: Some people may experience additional side effects when using pseudoephedrine, including: Anyone experiencing serious side effects from a nasal decongestant should seek urgent medical advice. Use of imidazolines (found in nasal decongestant sprays and eye drops) was tied to an approximate doubling of risk for an abnormal connection between the trachea and esophagus. Serious side effects have been reported with phenylephrine including the following: Phenylephrine can cause blurred vision. In the case of phenylephrine, there are no specific foods that you must exclude from your diet when receiving this medication. Dr. Sheila Goodman answered Specializes in Obstetrics and Gynecology OK Eccles, R. (2006). This medication comes in solution form and is instilled directly into the eye. However, on the flip side, some products may be severe and even life-threatening to both the mother and unborn fetus. WebSynthroid is FDA pregnancy category A - it is definitely secure for breastfeeding Synthroid or Levothyroxine in its generic form, is a a commonly used medication to treat Hypothyroidism, an underactive thyroid. I am a bot, and this action was performed automatically. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. To tackle cold-like symptoms, you can increase fluid intake, increase resting time, take warm baths and even use humidifiers. Press J to jump to the feed. trouble sleeping. Glad you feel better, I took that two nights in a row and it's on my safe list from the hospital. Phenylephrine is also known as: AH-Chew D, Biorphen, Congest Aid II, Contac-D, Despec-SF, Dimetapp Toddler's Drops Decongestant, Gilchew IR, Help I Have A Stuffy Nose, Little Colds Decongestant, Lusonal, Nasal Decongestant PE, Nasop, Nasop12, Neo-Synephrine, PediaCare Children's Decongestant, Phenyl-T, Ricobid-D, Sudafed PE Children's Nasal Decongestant, Sudafed PE Congestion, Sudogest PE, Suphedrine PE, Triaminic Thin Strips Cold with Stuffy Nose, Vazculep. In most cases, pregnant women may be subjected to various medications. I accidentally used phenylephrine hcl 0.25% hemorrhoid gel on my back (instead of hydrocortisone 1%). Dr. Allen Mitchell, the director of the Sloane Epidemiology Center at Boston University, conducted a study looking at babies born with birth defects from 1993 to 2010. Some research has suggested that using birth control pills near conception could increase the risk of low birth weight, preterm birth or urinary tract concerns in newborns. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Some of them may require surgery, but not all are life-threatening.. We avoid using tertiary references. They may recommend safer alternatives to help alleviate nasal congestion if required. Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Phenylephrine Pregnancy and Breastfeeding Warnings. They are both decongestants and have similar effects. I called my OB and they said there wasnt much they could do considering I already took the medicine (lol). Accidentally because I had a brain fart moment and forgot I was pregnant even though I know its not recommended during pregnancy So my rational brain is gone at the moment and Im freaking out that I could have harmed my baby. Label: 4 way fast acting phenylephrine hydrochloride spray [Fact sheet]. If you experience side effects, then stop using the drug, and see a doctor. It is usually administered by a healthcare provider immediately prior to eye examinations or procedures. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The drug may interact with other medications used by pregnant women, causing them much harm. Ok, so I have read here on BBC that phenylephrine is generally ok in small ammounts during 2nd and 3rd trimesters, but I couldn't help but worry myself. Nasal decongestants can cause some general side effects, the most common of which is insomnia. Press question mark to learn the rest of the keyboard shortcuts, Layperson/not verified as healthcare professional. https://www.uptodate.com/contents/search. There is a problem with We will discuss several reasons why it may not be advisable for pregnant mothers to use Sudafed PE or any phenylephrine-containing drug. Taking birth control pills during early pregnancy doesn't appear to increase the risk of birth defects. If you do conceive while taking a progestin-only birth control pill, sometime called the minipill, there is a slightly higher chance that the pregnancy will be ectopic. Enter multiple addresses on separate lines or separate them with commas. Mothers were asked about medications they took while pregnant and in the two months before becoming pregnant. Use of imidazolines (found in nazal decongestant sprays and eye drops) was tied to an almost double disk of an abnormal connection between the trachea and esophagus. information highlighted below and resubmit the form. Do not drive or operate heavy machinery until you know how phenylephrine affects you. -Routine use of acetaminophen during pregnancy is not advised. For these, please consult a doctor (virtually or in person). An illogical way to control methamphetamine abuse. Take one tablet every 4 hours when needed. The dose may be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye. Last updated on May 19, 2022. Signs and symptoms of SS can vary but may include: A person taking MAOIs needs to stop taking them for 14 days before starting a decongestant. Phenylephrine can also cause blurred vision. Store phenylephrine for injection at room temperature. the most helpful and trustworthy pregnancy and parenting information. I've done that with my last pregnancy and when I'm not pregnant. PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride solution/ drops, DailyMed: Current Medication Information; U.S. National Library of Medicine. This level means some animal studies suggest fetal risk but no human studies At 33 weeks of pregnancy both medications are fine to take. I personally hate this menthol effect because it burns my esophagus and stomach (which is why it didnt sit well with me) but I digress. Academic Research institutions, and allergy accidentally took phenylephrine while pregnant they took while pregnant and in meantime! May be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye studies academic! Of one or the other, not both flip side, some products may severe... 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